More Science, Less Fat®

Whether your practice already enjoys the benefits of offering the CoolSculpting Cryolipolysis® procedure to your patients or you simply want to learn more about this exciting new technology, we strive to keep you informed with our comprehensive clinical education programs.

CoolSculpting Scientific Studies and Publications

Based on early experiments conducted by scientists Dieter Manstein, MD, PhD and R. Rox Anderson, MD, of the Wellman Center of Photomedicine at Massachusetts General Hospital in Boston, a teaching affiliate of Harvard Medical School, Cryolipolysis®, the concept behind CoolSculpting, was invented.

Read about the CoolSculpting Cryolipolysis® procedure in the following peer-reviewed articles and clinical studies:

Safety and Efficacy of Submental Cryolipolysis

Bernstein, E.F., Bloom, J.D. Safety and Efficacy of Submental Cryolipolysis. JAMA Facial Plastic Surg.

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No Impact On Serum Lipid Levels & Liver Function

Klein, K. B., Bachelor, E. P., Becker, E. V. and Bowes, L. E. Multiple same day Cryolipolysis® treatments for the reduction of subcutaneous fat are safe. Lasers in Surg.

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Cryolipolysis® reduces excess adipose tissue

Nelson AA, Wasserman D, Avram MM. Cryolipolysis® for the Reduction of Excess Adipose Tissue. Semin Cutan Med Surg.

View abstract on PubMed

Efficacy & safety demonstrated in studies

Avram MM, Harry RS. Cryolipolysis® for Subcutaneous Fat Layer Reduction. Lasers Surg Med.

View abstract on PubMed

22% reduction in "love handles" fat layer

Dover J, Burns J, Coleman S, et al. A Prospective Clinical Study of Noninvasive Cryolipolysis® for Subcutaneous Fat Layer Reduction

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Proof of concept for Cryolipolysis®

Manstein D, Laubach H, Watanabe K, et al. Selective Cryolysis: A Novel Method of Noninvasive Fat Removal. Lasers Surg Med.

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Decreases fat and changes body contour

Zelickson B, Egbert BM, Preciado J, et al. Cryolipolysis® for Noninvasive Fat Cell Destruction: Initial Results From a Pig Model. Dermatol Surg.

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No impact on lipid & liver function

Klein KB, Zelickson B, Ropelle JG, et al. Noninvasive Cryolipolysis® for Subcutaneous Fat Reduction Does Not Affect Serum Lipid Levels or Liver Function Tests. Lasers Surg Med.

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No evidence of long-term nerve injury

Coleman SR, Sachdeva K, Egbert BM. Clinical Efficacy of Noninvasive Cryolipolysis® and Its Effects on Peripheral Nerves. Aesthetic Plast Surg.

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Visible improvement & high patient satisfaction

Dierickx CC, Mazer JM, Sand M, et al. Safety, Tolerance, and Patient Satisfaction With Noninvasive Cryolipolysis®. Dermatol Surg.

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Long-term follow-up shows lasting results

Bernstein EF. Longitudinal Evaluation of Cryolipolysis® Efficacy. J Cosmet Dermatol.

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Significant clinical practice business growth

Stevens WG, Pietrzak LK, Spring MA.Broad Overview of a Clinical and Commercial Experience With CoolSculpting. Aesthetic Surg J.

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Real Patients,
Real Results

Real Patients Real Results

Fat-reduction outcomes can improve patient satisfaction. See "before & after" evidence.


Patient Demand

Undeniable Patient Demand

Offering the CoolSculpting procedure will delight your patients and benefit your practice.


29 MILLION qualified prospective patients are seeking fat-reduction treatments* *ZELTIQ Data On File.